5-Chloro-N-(3-chlorophenyl)-2-hydroxybenzamide

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Identification

Molecular formula
C13H9Cl2NO2
CAS Number
66915-74-4
IUPAC Name
5-chloro-N-(3-chlorophenyl)-2-hydroxy-benzamide
Molecular Weight
280.12g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4645g/cm3
Appearance
is consistent with many aromatic amides.
Synonyms
22203-98-1
Interesting facts

Interesting Facts about 5-Chloro-N-(3-chlorophenyl)-2-hydroxy-benzamide

5-Chloro-N-(3-chlorophenyl)-2-hydroxy-benzamide, often referred to in research circles as an intriguing compound, has garnered attention due to its unique structure and potential applications. Here are some captivating insights:

  • Pharmacological Potential: This compound belongs to the class of benzamides, which are frequently studied for their biological activities, including antimicrobial and anti-inflammatory properties.
  • Diverse Substitution: The presence of multiple chlorine atoms in its structure suggests a significant impact on the compound's reactivity and biological interactions. Chlorinated compounds are noted for their enhanced lipophilicity, which can affect absorption and distribution in biological systems.
  • Hydroxyl Group Influence: The –OH (hydroxyl) functional group contributes to the compound’s ability to engage in hydrogen bonding, impacting solubility and biological activity. It may also play a role in the compound's mechanism of action against certain targets.
  • Structure Activity Relationship (SAR): Scientists often conduct SAR studies on benzamide derivatives to optimize their pharmacological profiles, making this compound a key subject for further medicinal chemistry research.
  • Environmental Impact: Compounds containing chlorine can pose ecological risks; thus, understanding their persistence and degradation pathways in the environment is crucial for sustainability considerations.

In conclusion, 5-Chloro-N-(3-chlorophenyl)-2-hydroxy-benzamide holds promise in various fields of research, and its unique characteristics make it an exciting subject for ongoing studies in medicinal chemistry and environmental science. As with many chemical compounds, the balance between efficacy and safety will determine its future applications.

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