5-Fluorouracil

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Identification

Molecular formula
C4H3FN2O2
CAS Number
51-21-8
IUPAC Name
5-fluoro-1-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
Molecular Weight
130.08g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4430g/cm3
Synonyms
5-Fluoro-2'-deoxyuridine
Interesting facts

Interesting Facts about 5-fluoro-1-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione

The compound 5-fluoro-1-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione is a fascinating member of the pyrimidine family, offering a unique combination of structural and functional characteristics. Here are some intriguing aspects of this compound:

  • Medicinal Potential: This compound has garnered interest in medicinal chemistry due to its structural similarity to nucleosides. Such compounds can exhibit antiviral and anticancer properties, making them potential candidates for therapeutic applications.
  • Fluorine Influence: The presence of fluorine in the structure can significantly enhance bioactivity. Fluorinated compounds often exhibit improved pharmacokinetic properties, which can lead to increased stability and bioavailability in drug formulation.
  • Hydroxymethyl Tetrahydrofuran: The inclusion of a tetrahydrofuran moiety adds to the structural complexity and can influence the compound’s interaction with biological systems. This functional group can facilitate various chemical reactions, enhancing the compound's versatility in synthesis.
  • Synthetic Relevance: The synthetic pathways to create this compound have implications for developing new heterocyclic compounds in the laboratory, showcasing the importance of fluorinated derivatives in organic chemistry.
  • Research Applications: Ongoing studies often explore the compound's potential in various fields, including agrochemicals and molecular biology, emphasizing its role as a versatile building block in organic synthesis.

In summary, 5-fluoro-1-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione is more than just a complex molecule; it represents a convergence of biological activity and synthetic chemistry that tantalizes scientists with its potential. As research continues, this compound may unlock new avenues in drug development and application.

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