5-methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide

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Identification

Molecular formula
C12H9F3N2O2
CAS Number
158718-47-9
IUPAC Name
5-methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide
Molecular Weight
256.21g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4100g/cm3
Synonyms
leflunomide
Interesting facts

Interesting Facts about 5-methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide

This fascinating compound, known for its complex structure, features a unique isoxazole ring, which is a five-membered ring containing both nitrogen and oxygen. The incorporation of the trifluoromethyl group is particularly noteworthy, as it significantly influences the compound's properties.

Key Features

  • Trifluoromethyl Substitution: The trifluoromethyl group (–CF3) not only enhances lipophilicity but also affects the electronic properties, making the compound an interesting candidate for medicinal chemistry.
  • Biological Activity: Isoxazole derivatives have shown potential in various biological applications, including anti-inflammatory and anti-cancer activities, making this compound worth investigating in pharmaceuticals.
  • Synthetic Versatility: The presence of multiple functional groups in the structure allows for diverse synthetic pathways, offering opportunities for structural modifications that can lead to new derivatives with enhanced efficacy.

Quote by a renowned chemist: "The beauty of organic chemistry lies in the imaginative transformations and the stories that each compound tells through its structure."

Research Implications

Researchers are intrigued by the potential applications of this compound in drug development. Its structural components may contribute to the creation of new therapeutic agents targeting specific diseases. The ability to modify the carboxamide group opens pathways for creating a library of compounds with varied biological profiles. Investigating the interactions of this compound with biological targets could lead to breakthroughs in treatment solutions.

In conclusion, 5-methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide is a prime example of how intricate chemical structures can lead to promising research avenues in chemistry and medicinal science.

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