Furazolidone

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Identification

Molecular formula
C8H7N3O5S
CAS Number
67-45-8
IUPAC Name
5-(methylsulfanylmethyl)-3-[(5-nitro-2-furyl)methyleneamino]oxazolidin-2-one
Molecular Weight
225.22g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4280g/cm3
Synonyms
MFCD00057257
Interesting facts

Interesting Facts about 5-(methylsulfanylmethyl)-3-[(5-nitro-2-furyl)methyleneamino]oxazolidin-2-one

This intriguing compound, known for its diverse applications in medicinal chemistry, combines both aromatic and heterocyclic structures, leading to enhanced biological activity. Let's delve into some fascinating aspects of this compound:

  • Pharmaceutical Relevance: The oxazolidinone structure is key to a class of antibacterial agents known as oxazolidinones, which are effective against various Gram-positive bacterial infections.
  • Mechanism of Action: The mechanism typically involves inhibition of bacterial protein synthesis, thereby preventing the growth of bacteria. This highlights its importance in combating antibiotic resistance.
  • Bioisosterism: The incorporation of the furan ring (5-nitro-2-furyl) makes this compound interesting for drug design, as such changes can enhance drug efficacy and reduce side effects.
  • Potential Applications: Beyond antibiotic properties, structural modifications may lead to potential applications in cancer therapy and anti-inflammatory treatments.
  • Research Opportunities: The synthetic pathways to create this compound can lead to exciting research avenues, focusing on novel synthesis techniques or exploring the effects of various substituents on biological activity.

In summary, 5-(methylsulfanylmethyl)-3-[(5-nitro-2-furyl)methyleneamino]oxazolidin-2-one encapsulates a wealth of chemical complexity and therapeutic potential. As scientific advancements continue, the exploration of this compound and its derivatives could yield significant contributions to both medicinal chemistry and pharmacology.

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