5,6-Dichloro-2-(trifluoromethyl)-1H-benzimidazole

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Identification

Molecular formula
C8H3Cl2F3N2
CAS Number
67914-60-7
IUPAC Name
5,6-dichloro-2-(trifluoromethyl)-1H-benzimidazole
Molecular Weight
266.00g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.6600g/cm3
Synonyms
2338-25-2
Interesting facts

Interesting Facts about 5,6-Dichloro-2-(trifluoromethyl)-1H-benzimidazole

The compound 5,6-dichloro-2-(trifluoromethyl)-1H-benzimidazole is a fascinating molecular entity with a variety of applications, particularly in the field of pharmaceuticals and agrochemicals. Its unique structure provides a rich platform for interaction due to the presence of halogen atoms which play a significant role in enhancing the compound's biological activity. Here are some captivating highlights:

  • Pharmaceutical Relevance: This compound is often explored for its potential as an antifungal and antiviral agent, demonstrating the importance of substituted benzimidazoles in medicinal chemistry.
  • Agricultural Applications: Its ability to inhibit fungal growth also makes it valuable in the agricultural sector, contributing to effective fungicide formulations.
  • Environmentally Friendly: Compounds like this one are designed to minimize environmental impact while maximizing effectiveness, aligning with the increasing demand for sustainable chemical solutions.
  • Research and Development: Ongoing studies focus on optimizing its properties, ranging from selectivity to toxicity, paving the way for the next generation of effective agents.

Structure-Activity Relationship

The structural features of 5,6-dichloro-2-(trifluoromethyl)-1H-benzimidazole enhance its lipophilicity and electronic characteristics. The trifluoromethyl group notably increases the compound's biological activity by improving the interaction with biological membranes, which is critical for its effectiveness.

Conclusion

In summary, 5,6-dichloro-2-(trifluoromethyl)-1H-benzimidazole represents a compound that bridges several fields, from pharmaceuticals to agrochemicals. Its intriguing properties and versatile applications make it a noteworthy subject of study in contemporary chemistry.

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