Coenzyme B12

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Identification

Molecular formula
C63H88CoN14O14P
CAS Number
13408-78-1
IUPAC Name
6-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethylsulfanyl]-4-hydroxy-6-oxo-hexanoic acid
Molecular Weight
1355.37g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
2.0500g/cm3
Synonyms
3-hydroxyhexanedioyl-CoA
Interesting facts

Interesting Facts about 6-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethylsulfanyl]-4-hydroxy-6-oxo-hexanoic acid

This compound, with its complex structure, represents a fascinating area of research in biochemical processes, particularly in the realms of pharmaceuticals and molecular biology. Its intricate arrangement of functional groups contributes significantly to its biological activity and potential therapeutic applications.

  • Biological Relevance: The presence of an aminopurine moiety connects it to nucleic acid metabolism, potentially influencing DNA and RNA synthesis or stability.
  • Phosphoryl Groups: The multiple phosphoryl groups might play a crucial role in biochemical signaling pathways, acting as a phosphate donor or participating in energy transfer processes.
  • Sulfanyl Group: The ethylsulfanyl group can be significant for enhancing solubility and reactivity, which may facilitate interaction with various biological targets.

In terms of research implications, this compound is a promising lead in drug development, especially in targeting diseases where nucleic acid manipulation is key. Scientists are particularly interested in how the stereochemistry and functional groups of such compounds can lead to selective binding with biological receptors, ultimately paving the way for innovative treatments.

As noted by one researcher, "The exploration of complex organic molecules like this opens doors to new hypotheses regarding drug design and molecular interaction." This compound stands as a testament to how intricate structures can lead to significant advances in understanding life at the molecular level.


In summary, 6-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethylsulfanyl]-4-hydroxy-6-oxo-hexanoic acid epitomizes the sophisticated nature of chemistry, blending together components that not only elucidate fundamental processes but also challenge researchers to understand their potential application in medicine.

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