Sunitinib

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Identification

Molecular formula
C22H27N3O4
CAS Number
557795-19-4
IUPAC Name
6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one
Molecular Weight
398.48g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3830g/cm3
Synonyms
vesnarinone
Interesting facts

Interesting Facts about 6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one

This compound is a fascinating member of the quinoline family, which is known for its diverse biological activities. The structural complexity of this compound lends itself to a myriad of intriguing properties and potential applications in various fields.

Key Features

  • Pharmacological Potential: Quinoline derivatives have been extensively studied for their pharmacological properties, including their roles as potential anti-cancer agents, anti-inflammatory drugs, and anti-viral compounds.
  • Structural Motifs: The inclusion of a piperazine moiety is noteworthy as this structural feature is often found in many pharmacologically active compounds, enhancing receptor binding and biological activity.
  • Dimethoxy Group: The 3,4-dimethoxybenzoyl group contributes to the lipophilicity of the compound, which can significantly influence its absorption and distribution in biological systems.

Applications in Research

Given its intricate molecular architecture, this compound is often explored in:

  • Drug Discovery: Researchers are particularly interested in derivatives of this compound for developing new therapeutic agents.
  • Medicinal Chemistry: Its unique structure serves as a valuable template for the synthesis of new ligand analogs that may exhibit enhanced biological activities.

Quote to Consider

As stated by a prominent chemist, "The beauty of medicinal chemistry lies in the endless possibilities of modification and the resulting diversity in function." This compound exemplifies this philosophy.

In conclusion, 6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one stands as a testament to the intricate interplay between structure and function in the realm of chemical compounds. Its ongoing study is essential for advancing knowledge in both chemistry and pharmacology.

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