Azithromycin

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Identification

Molecular formula
C38H72N2O12
CAS Number
83905-01-5
IUPAC Name
6-[4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-12,13-dihydroxy-4-(5-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl)oxy-7-methoxy-3,7,9,11,13,14-hexamethyl-oxacyclotetradecane-2,10-dione
Molecular Weight
748.98g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1800g/cm3
Interesting facts

Overview of 6-[4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-12,13-dihydroxy-4-(5-hydroxy-4-methoxy-6-methyl-tetrahydropyran-2-yl)oxy-7-methoxy-3,7,9,11,13,14-hexamethyl-oxacyclotetradecane-2,10-dione

This complex and intriguing compound is a member of a diverse class of chemical entities known for their biological activity and structural sophistication. It is particularly noteworthy for its unique combination of functional groups and cyclic structures, which suggest potential applications in medicinal chemistry and pharmaceuticals.

Key Features:

  • Structural Complexity: The compound features a hexamethylated oxacyclotetradecane framework, which is notable for its unusual arrangement of methoxy and hydroxyl groups that can significantly influence its chemical reactivity and biological interactions.
  • Dimethylamino Group: The presence of a dimethylamino group is often linked to enhanced solubility and bioactivity, making it a valuable modification in drug design.
  • Tetrahydropyran Rings: The inclusion of tetrahydropyran rings contributes to the stereochemical diversity of the compound, which is known to affect how molecules interact with biological targets, potentially leading to various therapeutic effects.
  • Hydroxyl Groups: Multiple hydroxyl groups present in this compound could enhance its hydrogen-bonding ability, affecting its pharmacokinetics and binding affinity to biological receptors.

Scientists are particularly interested in compounds like this due to their potential in developing new treatments. As the famous biochemist Jerome Karle once said, “Every chemical compound has the potential to be a building block for medications that can change lives.” The extensive modifications to this compound hint at targeted activity, making it a candidate for further research into its therapeutic applications.

Future Directions:

Given the compound's unique structure, further studies could explore:

  • Its antimicrobial properties by screening against various pathogens.
  • The toxicity profile to assess safety and delineate therapeutic windows.
  • Its mechanism of action in biological systems to uncover potential therapeutic pathways.

In summary, the intricate architecture and functional versatility of this compound position it as an exciting subject for continued research and discovery.

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