6-Chloro-2-phenyl-1H-benzimidazole hydrate

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Identification

Molecular formula
C13H9ClN2 · H2O
CAS Number
6875-40-5
IUPAC Name
6-chloro-2-phenyl-1H-benzimidazole;hydrate
Molecular Weight
260.70g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3000g/cm3
Synonyms
1H-BENZIMIDAZOLE, 5-CHLORO-2-PHENYL-, HYDRATE
Interesting facts

Interesting Facts about 6-Chloro-2-phenyl-1H-benzimidazole Hydrate

6-Chloro-2-phenyl-1H-benzimidazole hydrate is a fascinating compound that has sparked interest among chemists for its unique structure and potential applications. Here are some notable aspects:

  • Structural Significance: The compound features a benzimidazole core, which is known for its involvement in various biological activities, particularly in medicinal chemistry.
  • Substituents Matter: The presence of a chlorine atom at the 6-position and a phenyl group at the 2-position contributes to its chemical reactivity and influences how the compound interacts with biological targets.
  • Biological Activity: Compounds containing the benzimidazole framework, like this hydrate, are often investigated for their antimicrobial, antifungal, and antiparasitic properties. This makes them valuable in pharmaceutical research.
  • Hydration Importance: The inclusion of water molecules in its hydrate form can affect the compound's stability and solubility, which are critical factors in drug formulation and efficacy.
  • Research and Development: Scientists are continually exploring derivatives of benzimidazole compounds for potential use in treating conditions such as cancer and infections, making this compound relevant in ongoing medicinal research.

As noted chemist Albert Hofmann once said, "Science is a way of trying not to fool yourself." The study of 6-chloro-2-phenyl-1H-benzimidazole hydrate exemplifies this, as researchers aim to uncover the true potential of such compounds while adhering to rigorous scientific principles.

This compound not only showcases the beauty of organic chemistry but also the interconnectedness of structure and function in drug design, illustrating how slight modifications can lead to significant changes in biological activity.

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