Dexamethasone

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Identification

Molecular formula
C22H29FO5
CAS Number
50-02-2
IUPAC Name
6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Molecular Weight
392.46g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4280g/cm3
Synonyms
6.alpha.-Fluoroprednisolone
Interesting facts

Interesting Facts About 6-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

This compound, commonly referred to in scientific literature as a derivative of a steroid, showcases remarkable structural features that contribute to its biological activity.

Biological Significance

The presence of the fluoro group at the 6-position is notable as it enhances the compound's potency. This modification can lead to increased receptor binding affinity, which is crucial in therapeutic applications, particularly in:

  • Anti-inflammatory treatments
  • Hormonal therapies
  • Cancer research

Chemical Modifications

Within its structure, the compound integrates various functional groups, including:

  • Hydroxy groups: These contribute to the compound's solubility and reactivity.
  • A ketone group: This can play a vital role in its metabolic pathways.

Such modifications are often strategically employed in medicinal chemistry to optimize the desired biological effects while minimizing side effects.

Analytical Methods

Researchers often utilize advanced analytical techniques to study compounds like this one, including:

  • Nuclear Magnetic Resonance (NMR): For structural elucidation.
  • Mass Spectrometry (MS): To determine molecular weight and structure.
  • Chromatography: For purification and separation.

Research and Development

Ongoing investigations into this compound's pharmacological properties highlight its potential in:

  • Drug discovery: Identifying new therapeutic agents.
  • Molecular modeling: Predicting interactions within biological systems.

As a scientist or a chemistry student, exploring such diversified chemical entities enhances not only our understanding of organic chemistry but also opens doors to novel therapeutic avenues.

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