6-(trifluoromethoxy)-1,3-benzothiazol-2-amine

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Identification

Molecular formula
C8H5F3N2OS
CAS Number
198569-10-9
IUPAC Name
6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
Molecular Weight
232.21g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5160g/cm3
Synonyms
riluzole
Interesting facts

Interesting Facts about 6-(Trifluoromethoxy)-1,3-benzothiazol-2-amine

6-(Trifluoromethoxy)-1,3-benzothiazol-2-amine is a fascinating compound notable for its unique structural features and applications in various fields. Here are some engaging insights:

  • Fluorine Chemistry: The presence of trifluoromethoxy groups (–O—CF3) introduces significant reactivity and lipophilicity. This specific configuration enhances the compound's ability to interact with biological targets, often leading to increased potency.
  • Pharmaceutical Relevance: Compounds containing benzothiazole moieties have been widely studied for their potential therapeutic applications, particularly as anti-cancer and anti-inflammatory agents. The structural modifications, like the addition of the trifluoromethoxy group, can fine-tune the biological activity.
  • Environmental Chemistry: The trifluoromethoxy group not only alters the compound's chemical behavior but also its environmental stability. This raises important discussions in environmental science regarding the persistence of fluorinated compounds in ecosystems.
  • Synthesis and Methods: The synthesis of 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine typically involves advanced synthetic strategies. Techniques such as nucleophilic substitution and coupling reactions are often employed, making it a compelling subject for those interested in organic synthesis.
  • Research Potential: Given its unique properties, ongoing research may unveil new applications of this compound. It presents opportunities for the development of novel drugs and materials, sparking interest among chemists aiming to modify and explore such structures.

In summary, 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine encapsulates the essence of how subtle changes in molecular structure can lead to diverse and significant implications in both chemistry and medicine. Its study not only enhances our understanding of chemical interactions but also paves the way for innovative discoveries.

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