Dexamethasone

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Identification

Molecular formula
C22H29FO5
CAS Number
50-02-2
IUPAC Name
(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular Weight
392.46g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1570g/cm3
Synonyms
flumethasone
Interesting facts

Interesting Facts about (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

This complex compound, known for its structured framework, is a fascinating example of how intricate molecular arrangements can lead to significant biological activity. Here are some noteworthy points:

  • Steroid-like Framework: The compound has a steroid-like backbone, which is common in many biologically active molecules.
  • Fluorine Substituents: The presence of fluorine atoms can enhance the compound’s biological activity and metabolic stability, making it a prime candidate for pharmaceutical development.
  • Hydroxy Groups: The two hydroxy groups contribute to its potential hydrophilicity, influencing its interactions with biological systems.
  • Biological Activity: Such compounds often exhibit properties such as anti-inflammatory, anti-cancer, or antiviral effects, showcasing their potential in therapeutic applications.

Furthermore, its stereochemistry, indicated by the specific R and S configurations, plays a crucial role in the compound’s biological interactions. As chemists often say, “The function of a compound is influenced by its structure,” and this compound is a perfect illustration of that principle. Each stereocenter contributes to how this molecule orients itself in a biological environment, impacting how it interacts with enzymes and receptors within living organisms.

As a testament to its complexity and potential, research into compounds like this one continues to unveil new insights into medicinal chemistry and the development of novel therapeutics.

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