Dexamethasone

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Identification

Molecular formula
C22H29FO5
CAS Number
50-02-2
IUPAC Name
(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Molecular Weight
392.46g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3000g/cm3
Synonyms
paramethasone
Interesting facts

Interesting Facts About (6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

This compound, a complex steroid-like structure, showcases the fascinating interplay of synthetic and natural chemistry. Its intricate design suggests significant biological activity, making it a subject of interest in medicinal chemistry and pharmacology. Here are some engaging facts about this compound:

  • Fluorine Incorporation: The introduction of fluorine in pharmaceuticals can enhance metabolic stability and lipophilicity, potentially leading to improved bioactivity.
  • Hydroxyl Groups: Exhibiting dihydroxy functional groups, this compound may interact with biological systems via hydrogen bonding or enzyme inhibition.
  • Stereoisomerism: The multiple stereocenters highlight the significance of chirality in drug design, as different isomers can exhibit profoundly different pharmacological effects.
  • Cyclopenta[a]phenanthrene Framework: This unique ring system is related to a class of compounds that are often biologically active and can mimic steroid hormones.
  • Applications: Due to its structure, the compound may have potential applications in treating hormonal disorders or certain types of cancers, warranting further investigation.

In summary, this compound not only offers a glimpse into the complexity of chemical design but also serves as an excellent example of the potential advancements in therapeutic applications that can arise from detailed structural modifications. In the words of a famous chemist, "The only difference between science and art is the question of what is to be considered a successful outcome." This compound holds promise, reflecting the artistry involved in creating useful compounds in the realm of chemistry.

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