Dexamethasone

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Identification

Molecular formula
C22H29FO5
CAS Number
50-02-2
IUPAC Name
(6S,9R,16R)-6,9-difluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one
Molecular Weight
392.46g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3230g/cm3
Synonyms
NS00002092
Interesting facts

Interesting Facts about (6S,9R,16R)-6,9-difluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one

This compound, known for its complex structure and biological significance, represents an intriguing area of study within the realm of medicinal chemistry. Below are some fascinating insights into its properties and potential applications:

  • Steroidal Framework: The compound belongs to a class of steroids, which are key players in numerous biological processes, including the regulation of metabolism and immune response.
  • Fluorination Influence: The incorporation of fluorine atoms in its structure makes this compound unique, as fluorination can enhance biological activity and improve metabolic stability, influencing how the compound interacts with biological systems.
  • Hydroxyl Groups: The presence of hydroxyl groups in the molecule is known for imparting polar characteristics, which can impact the solubility and bioavailability of the compound, thus playing a pivotal role in drug design.
  • Potential Therapeutic Applications: Research on related compounds suggests that modifications similar to those in this molecule could lead to the development of therapeutics aimed at treating diseases such as cancer or hormonal disorders.
  • Complex Synthesis: The synthesis of compounds with such a sophisticated atomic arrangement often requires intricate chemical reactions and advanced techniques, making them a challenge yet a rewarding focus for chemists.

The exploration of (6S,9R,16R)-6,9-difluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one exemplifies the sophisticated intersection of structure, function, and synthetic methodology in chemistry. As we continue to unravel the complexities of such compounds, we move closer to unlocking their vast potential in various fields, including pharmaceuticals, agriculture, and beyond.

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