lisinopril

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Identification

Molecular formula
C21H31N3O5
CAS Number
83915-83-7
IUPAC Name
7-[(1-ethoxycarbonyl-3-phenyl-propyl)amino]-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylic acid
Molecular Weight
441.52g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4507g/cm3
Synonyms
104013-57-2
Interesting facts

Interesting Facts about 7-[(1-ethoxycarbonyl-3-phenyl-propyl)amino]-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylic acid

This compound represents a fascinating area of study due to its structural complexity and potential applications in medicinal chemistry. Here are some intriguing aspects:

  • Multifunctional Structure: The compound features multiple functional groups, including carboxylic acids and amines, making it an excellent candidate for various biological activities.
  • Potential Pharmacological Applications: Compounds with similar structures are often investigated for their therapeutic properties, especially in treating neurological disorders. Their ability to cross the blood-brain barrier is of significant interest.
  • Sp3 Hybridization: The presence of potential chiral centers in the structure allows for the exploration of stereochemistry, which can lead to different biological activities depending on their orientation.

The unique octahydropyridazino scaffold in this compound is noteworthy. It is considered a scaffold which can enhance the binding affinity towards various biological targets. Additionally, the combination of the phenyl and ethoxycarbonyl functionalities can influence the lipophilicity and thus the pharmacokinetic properties of the entire molecule. Scientists often emphasize that understanding the interplay between structure and activity is key in drug discovery.

Overall, this compound exemplifies the complexity of molecular design in creating potential pharmaceuticals. As stated by a prominent chemist, “The beauty of chemistry lies not just in the molecules we create but in the vast potential they hold.”

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