Abacavir

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Identification

Molecular formula
C14H18N6O
CAS Number
136470-78-5
IUPAC Name
7-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one
Molecular Weight
286.33g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3700g/cm3
Interesting facts

Interesting Facts about 7-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one

This intriguing compound is a member of the pyrrolopyrimidine class, which is known for its biological significance and diverse applications in medicinal chemistry. Below are some fascinating aspects of this compound:

  • Biological Activity: Many compounds within the pyrrolopyrimidine family, including this one, exhibit notable biological activities, often functioning as potent inhibitors for various enzymes and receptors.
  • Potential Drug Development: Compounds similar to this one have shown promise in drug development processes, particularly in targeting cancer and other disease pathways due to their ability to modulate cellular functions.
  • Sugar Moiety: The incorporation of a sugar-like structure, specifically the tetrahydrofuran unit in this compound, enhances solubility and bioavailability, which are crucial for pharmacological efficacy.
  • Structure-Activity Relationship (SAR): The distinct functional groups present, such as the hydroxymethyl and hydroxyl groups, contribute to the overall reactivity and selectivity of the compound, making it a key target in SAR studies.
  • Versatile Functionalization: The presence of multiple functional groups allows for possible modifications, which can help in fine-tuning the compound's therapeutic profile and reducing side effects.

In conclusion, the structural complexity and potential biological roles of 7-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one make it a fascinating subject of study in the realms of organic and medicinal chemistry. With ongoing research, compounds like this could lead to the discovery of novel therapeutic agents.

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