Loprazolam

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Identification

Molecular formula
C16H11ClN4O2
CAS Number
61197-73-7
IUPAC Name
7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
Molecular Weight
383.25g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4000g/cm3
Synonyms
oxazepam
Interesting facts

Interesting Facts about 7-Chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one

The compound 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one is a fascinating member of the benzodiazepine family, which is well known for its psychoactive properties. This compound stands out for several reasons:

  • Psychoactive Potential: Benzodiazepines are primarily recognized for their role as anxiolytics, sedatives, and muscle relaxants. Given the structure of this compound, it may exhibit potential properties in mental health and therapeutic applications.
  • Structural Complexity: The presence of both a hydroxyl group and a chloro substituent contributes to its pharmacological profile. The complex structure allows for diverse interactions with biological targets.
  • Research Relevance: Compounds like this one are of great interest in medicinal chemistry. They are often studied for their interaction with GABAA receptors, which play a crucial role in inhibitory neurotransmission across the brain.
  • Pharmaceutical Applications: There is ongoing research into how derivatives of benzodiazepines can be optimized for better efficacy, fewer side effects, and potential applications in conditions like anxiety, insomnia, and seizures.
  • Innovative Synthesis: The synthesis of benzodiazepines often involves intricate multi-step organic reactions, making them a popular subject of study for students and chemists alike.

As one delves into the chemistry of this compound, it's evident that the intersection of structure and function offers invaluable insights into drug development. As Nobel Prize winner Mario Molina once said, “Chemistry knows no borders,” and the exploration of diverse compounds like this one certainly embodies that spirit!


Whether you're a budding chemistry student or an experienced researcher, the realm of benzodiazepines continues to present remarkable opportunities for discovery and innovation.

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