Lorazepam

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Identification

Molecular formula
C15H10Cl2N2O2
CAS Number
846-49-1
IUPAC Name
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
Molecular Weight
321.16g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3120g/cm3
Synonyms
lorazepam
Interesting facts

Interesting Facts about 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one

The compound 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one is a fascinating member of the benzodiazepine family, which is well-known for its anxiolytic, sedative, and muscle-relaxing properties. Here are some intriguing points to consider:

  • Pharmacological Applications: This compound, like many benzodiazepines, plays a significant role in medicine. Benzodiazepines are primarily used to treat anxiety, insomnia, and certain types of seizures.
  • Chlorine Substituents: The presence of chlorine atoms in its structure enhances its pharmacological activity and potency. This highlights the importance of molecular modifications in drug design.
  • Hydroxy Group Influence: The hydroxy group at position 3 is crucial; it often influences the compound's interaction with biological targets and enhances its solubility.
  • Synthetic Interest: Chemists are continuously exploring various synthetic routes to develop derivatives of this compound, aiming to improve efficacy and minimize side effects.
  • Structure-Activity Relationship (SAR): The study of this compound exemplifies SAR in medicinal chemistry, providing insights on how structural changes can affect biological activity.

This compound embodies the delicate balance between chemistry and pharmacology, illustrating how modifications at the molecular level lead to significant therapeutic benefits. As a student or researcher, understanding the complexities of such compounds can enhance your knowledge of drug development and the intricate workings of medicinal chemistry.

In the words of a well-known chemist, "The beauty of chemistry lies in its structure and the stories it tells about interactions and functions." This compound is a perfect example of such stories, bridging the gap between chemical structure and biological function.

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