Diazepam

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Identification

Molecular formula
C16H12ClFN2O
CAS Number
439-14-5
IUPAC Name
7-chloro-5-(2-fluorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
Molecular Weight
284.71g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3060g/cm3
Synonyms
17617-60-6
Interesting facts

Interesting Facts About 7-chloro-5-(2-fluorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one

This compound belongs to the benzodiazepine family, known for their numerous applications in medicine, particularly as anxiolytics, sedatives, and muscle relaxants. Here are some key points to consider:

  • Pharmacological Importance: Compounds in the benzodiazepine class are widely studied for their effects on the central nervous system. This particular compound has intriguing modifications that could potentially enhance its therapeutic profile.
  • Structural Features: The presence of both a chloro and a fluoro substituent offers unique properties, as halogens can significantly influence the compound's activity and binding affinity at receptors.
  • Potential Applications: Research is ongoing into the anxiety-relieving properties and possible neuroprotective effects of derivatives such as this one. The hydroxy group adds to the compound's complexity and might play a role in its biological interactions.
  • Synthetic Routes: The synthesis of such complex structures often involves multi-step processes, showcasing the innovation of synthetic organic chemistry. Scientists consistently seek efficient pathways to improve yield and reduce costs.

The study of benzodiazepines like 7-chloro-5-(2-fluorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one raises fascinating questions about structure-activity relationships (SAR) and how minor structural changes can lead to significant variations in pharmacological effects. As a scientist, understanding these relationships is crucial for developing more effective drugs with fewer side effects.

In conclusion, this compound is a prime example of how synthetic chemistry intersects with pharmacology, demonstrating the importance of chemical innovation in developing next-generation therapies.

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