Ascofuranone

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Identification

Molecular formula
C23H24O4
CAS Number
82520-59-2
IUPAC Name
7-hydroxy-11a-methyl-3,3a,3b,4,5,9b,10,11-octahydronaphtho[2,1-e]isobenzofuran-1-one
Molecular Weight
354.42g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2813g/cm3
Synonyms
NCIOpen2_005820
Interesting facts

Interesting Facts about 7-Hydroxy-11a-methyl-3,3a,3b,4,5,9b,10,11-octahydronaphtho[2,1-e]isobenzofuran-1-one

This complex organic compound belongs to the category of octahydronaphthofuran derivatives and exhibits various intriguing properties that make it a subject of interest in both chemistry and pharmacology.

Structural Features

Its detailed structure enables a wide range of interactions with biological systems. Key features include:

  • Multi-ring structure: The compound comprises an intricate system of fused rings that provide stability and influence its reactivity.
  • Hydroxyl groups: The presence of hydroxyl functional groups contributes to its potential for hydrogen bonding, which is vital for its biological activity.
  • Chiral centers: With chiral carbons present, this compound can exhibit different stereoisomers, impacting its pharmacological effects significantly.

Biological Significance

7-Hydroxy-11a-methyl-3,3a,3b,4,5,9b,10,11-octahydronaphtho[2,1-e]isobenzofuran-1-one has garnered attention for its potential therapeutic applications. Here are some areas where it plays a role:

  • Antioxidant Activity: Studies suggest that compounds with similar structures might exhibit significant antioxidant properties, which can be beneficial in preventing oxidative stress.
  • Neuroprotective Effects: Certain derivatives of octahydronaphthofuran have been explored for their ability to protect neurons against various forms of damage.
  • Potential as Drug Candidates: Its unique structure might lead to novel drug design, particularly in treating neurodegenerative diseases.

Research Potential

This compound serves as a model for investigating complex organic synthesis and offers opportunities in:

  • Drug Formulation: Researchers are keen to explore how modifications in the structure influence pharmacodynamics and pharmacokinetics.
  • Natural Product Synthesis: Its naturally occurring relatives might provide insights into biosynthetic pathways and ecological roles.

In conclusion, 7-hydroxy-11a-methyl-3,3a,3b,4,5,9b,10,11-octahydronaphtho[2,1-e]isobenzofuran-1-one stands out due to its structural complexity and potential applications in various fields, indicating that ongoing research could unlock even more of its secrets.

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