7-Nitro-8-quinolyl 3-(2-chlorophenyl)-2-methylprop-2-enoate
- Molecular formula
- C19H13ClNO4
- CAS Number
- 2761-09-3
- IUPAC Name
- (7-nitro-8-quinolyl) 3-(2-chlorophenyl)-2-methyl-prop-2-enoate
- Molecular Weight
- 366.78g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.4060g/cm3
Identification
Exploring (7-nitro-8-quinolyl) 3-(2-chlorophenyl)-2-methyl-prop-2-enoate
(7-nitro-8-quinolyl) 3-(2-chlorophenyl)-2-methyl-prop-2-enoate is a fascinating compound that combines the intriguing structures of quinoline and acrylic esters. This compound stands out in both synthetic chemistry and pharmacological research due to its unique chemical properties and potential applications.
Key Features
- Biological Activity: Compounds with quinoline cores are often recognized for their diverse biological activities. They may possess antimalarial, antibacterial, or anticancer properties, making them of high interest in medicinal chemistry.
- Synthetic Versatility: The presence of the acrylic moiety in this compound allows for further modifications. Chemists can utilize this feature to create a variety of derivatives that could enhance or alter its biological activity.
- Structure-Activity Relationship (SAR): Understanding how the molecular structure affects the biological activity of (7-nitro-8-quinolyl) 3-(2-chlorophenyl)-2-methyl-prop-2-enoate is crucial. Researchers often explore different substituents around the quinoline scaffold to optimize efficacy.
The synthesis of this compound typically involves a strategic coupling of the quinoline derivative with the acrylic ester, highlighting the importance of both traditional and modern synthetic techniques. By modifying the substituents on the aromatic rings, scientists can explore a plethora of derivatives, allowing for an extensive range of research possibilities.
Quote from Research:
"Compounds like (7-nitro-8-quinolyl) 3-(2-chlorophenyl)-2-methyl-prop-2-enoate serve as excellent scaffolds for improving bioactivity through systematic structural modifications." —Journal of Medicinal Chemistry
In conclusion, (7-nitro-8-quinolyl) 3-(2-chlorophenyl)-2-methyl-prop-2-enoate exemplifies the versatility and potential within the realm of synthetic organic chemistry, as well as its implications in drug discovery. Its continued study may unveil new therapeutic agents and contribute to advancing pharmacological science.