Chlorpromazine

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Identification

Molecular formula
C17H19ClN2OS
CAS Number
50-53-3
IUPAC Name
8-chloro-10-[3-(dimethylamino)propyl]phenothiazin-3-ol
Molecular Weight
318.86g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3000g/cm3
Synonyms
7-Hydroxychlorpromazine
Interesting facts

Interesting Facts about 8-Chloro-10-[3-(dimethylamino)propyl]phenothiazin-3-ol

8-Chloro-10-[3-(dimethylamino)propyl]phenothiazin-3-ol is a fascinating compound that belongs to the phenothiazine family, a group notorious for its structural diversity and wide range of applications. Phenothiazines have made headlines in the field of pharmacology, being primarily recognized for their role as antipsychotic medications.

Here are some key points regarding this unique compound:

  • Pharmacological Significance: This compound is notable for its potential therapeutic applications, particularly in the treatment of psychiatric disorders. Its structure allows it to interact with various neurotransmitter systems, primarily dopamine and serotonin receptors.
  • Research Implications: The unique arrangement of the chlorine atom and the dimethylamino group facilitates extensive research into its biological effects. Studies that explore its mechanism of action can lead to better drug design and more effective treatments.
  • Historical Context: Phenothiazines were first discovered in the 1930s and have since evolved into a crucial class of pharmaceuticals. This compound's variation might contribute to the body of knowledge regarding drug efficacy and side-effect profiles.
  • Synthetic Pathways: The synthesis of this compound involves multi-step processes which can be quite instructive for chemistry students interested in organic synthesis techniques, elaborating on modern synthetic methods and their applications.
  • Potential for Structural Modification: Researchers often explore structural modifications in phenothiazines to enhance their efficacy and reduce side effects. The presence of a dimethylamino propyl side chain provides a good scaffold for such modifications.

As noted by scientists in the field, “Understanding the interaction of phenothiazine derivatives with target receptors is key to unlocking new pharmaceutical possibilities.” This compound, with its structural complexity, serves as a critical focal point for research on drug interactions and the development of next-generation psychotropics.

In conclusion, 8-Chloro-10-[3-(dimethylamino)propyl]phenothiazin-3-ol stands as more than just a chemical structure; it embodies the convergence of chemistry, medicine, and research, making it a compelling subject for both theoretical study and practical applications.

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