Vorinostat

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Identification

Molecular formula
C14H20N2O3
CAS Number
149647-78-9
IUPAC Name
8-oxo-8-[4-(4-phenylpiperazin-1-yl)phenyl]octanehydroxamic acid
Molecular Weight
264.32g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1180g/cm3
Synonyms
CHEMBL99216
Interesting facts

Interesting Facts About 8-oxo-8-[4-(4-phenylpiperazin-1-yl)phenyl]octanehydroxamic Acid

8-oxo-8-[4-(4-phenylpiperazin-1-yl)phenyl]octanehydroxamic acid is a fascinating compound in the realm of medicinal chemistry and pharmacology. This compound is particularly noteworthy for its potential applications in the treatment of a range of diseases, including neurological disorders.

Key Highlights:

  • Neuropharmacological Potential: The structural features of this compound suggest that it can interact with key neurotransmitter systems, possibly making it a candidate for drugs targeting anxiety, depression, and other mood disorders.
  • Oxime Functionality: The hydroxamic acid moiety in 8-oxo-8-[4-(4-phenylpiperazin-1-yl)phenyl]octanehydroxamic acid is known for its ability to chelate metal ions, which can be crucial in biochemical pathways. This property has applications in drug design and understanding enzyme mechanisms.
  • Structural Complexity: The presence of both the piperazine and phenyl groups contributes to the compound's lipophilicity, enhancing its membrane permeability, which is vital for its efficacy as a therapeutic agent.
  • Research Opportunities: As a relatively novel compound, it presents a variety of research avenues, from synthesis challenges to biological assays, allowing future scientists to explore its full potential.

In summary, 8-oxo-8-[4-(4-phenylpiperazin-1-yl)phenyl]octanehydroxamic acid embodies a blend of chemical elegance and therapeutic promise. As we continue to delve deeper into its properties, we may uncover new insights that could lead to groundbreaking treatments in modern medicine.

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