Cortisone

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Identification

Molecular formula
C21H28O5
CAS Number
53-06-5
IUPAC Name
(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Molecular Weight
360.44g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3000g/cm3
Synonyms
hydrocortisone
Interesting facts

Interesting Facts About (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

This compound represents a fascinating entry in the realm of organic chemistry, particularly due to its structural complexity and potential biological significance. Here are some key points about this molecule:

  • Stereochemistry: The compound features multiple stereocenters (8S, 9S, 10R, 11S, 13S, 14S, 17R), highlighting its chiral nature. This chirality is crucial for understanding its interactions in biological systems, as differing stereoisomers can exhibit vastly different biological activity.
  • Functional Groups: The presence of hydroxyl groups (-OH) and a hydroxyacetyl moiety not only contributes to the molecule's polarity and reactivity but also suggests potential for pharmacological applications, possibly influencing parameters like solubility and bioavailability.
  • Potential Applications: Compounds similar to this one have been explored in medicinal chemistry, particularly in drug development against a variety of diseases. The unique arrangement of functional groups could lend itself to applications in hormone therapy or cancer treatment, showcasing the importance of structural variations in drug design.
  • Natural Occurrence: Such complex organic compounds often mimic hormones or other naturally occurring substances, suggesting that they may be of natural origin or inspiration. Researchers can derive insights on biological processes through studying such compounds.
  • Biochemical Pathways: Understanding how this compound interacts within biochemical pathways could unveil new therapeutic targets for diseases associated with hormonal imbalances or other metabolic disorders.

In summary, the intricacies of this compound not only illustrate the beauty of organic chemistry but also emphasize the broader implications in medicinal science, making it an exciting topic of study for aspiring chemists and researchers alike. As stated by renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas," and this compound serves as a testament to the endless possibilities in the field of chemistry.

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