Amsacrine

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Identification

Molecular formula
C21H19FN4O
CAS Number
51264-14-3
IUPAC Name
9-amino-N-[2-(dimethylamino)ethyl]-5-fluoro-acridine-4-carboxamide
Molecular Weight
393.45g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3708g/cm3
Synonyms
5-fluoro-9-amino-(n-(2-dimethylamino)ethyl)acridine-4-carboxamide
Interesting facts

Interesting Facts about 9-amino-N-[2-(dimethylamino)ethyl]-5-fluoro-acridine-4-carboxamide

9-amino-N-[2-(dimethylamino)ethyl]-5-fluoro-acridine-4-carboxamide, commonly referred to in the scientific community as an acridine derivative, is a compound of significant interest due to its potential applications in the field of medicinal chemistry and drug development. Below are some noteworthy aspects of this fascinating compound:

  • Fluorine's Role: The presence of fluorine within the acridine structure enhances the compound's pharmacokinetic properties, including its solubility and bioavailability.
  • Mechanism of Action: This compound may interact with DNA, which is a common mechanism among many anticancer agents, leading to its potential use in therapeutic applications.
  • Dimethylamino Group: The dimethylamino moiety plays a crucial role in increasing the basicity of the compound, which can enhance interactions with biological targets.
  • Research Interest: Studies have indicated that acridine derivatives exhibit interesting biological activities, including antitumor, antibacterial, and anti-inflammatory effects, making this compound a valuable candidate for further research.
  • Structure-Activity Relationship: The unique combination of amino, fluoro, and acridine functionalities can lead to varied biological activities, emphasizing the importance of understanding structure-activity relationships in drug design.

As we delve deeper into the capabilities of 9-amino-N-[2-(dimethylamino)ethyl]-5-fluoro-acridine-4-carboxamide, it becomes clear that the compound stands as a promising scaffold for future medicinal applications. Its complexities exemplify the intricate connections between chemical structure and biological function, a core theme in the field of chemistry.

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