Carmustine

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Identification

Molecular formula
C10H19Cl2N3O2
CAS Number
154-93-8
IUPAC Name
aziridin-1-yl-[3-[bis(2-chloroethyl)amino]-4-methyl-phenyl]methanone
Molecular Weight
214.06g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5200g/cm3
Synonyms
21447-86-9
Interesting facts

Interesting Facts about Aziridin-1-yl-[3-[bis(2-chloroethyl)amino]-4-methyl-phenyl]methanone

Aziridin-1-yl-[3-[bis(2-chloroethyl)amino]-4-methyl-phenyl]methanone is a fascinating compound that combines several intriguing features. Here are some interesting aspects to consider:

  • Structural Complexity: This compound showcases an aziridine ring, a three-membered cyclic amine known for its unique reactivity. Such rings can participate in various chemical reactions, making them valuable in synthetic chemistry.
  • Biological Relevance: The presence of the bis(2-chloroethyl)amino group is reminiscent of certain chemotherapeutic agents, particularly alkylating agents that have been used in cancer treatment. Such structures work by disrupting DNA, thereby impeding cell division.
  • Pharmaceutical Applications: Compounds with similar structures have been studied for their potential in drug design. They may offer insights into developing targeted therapies, especially in oncology.
  • Reactivity: The aziridinyl moiety can undergo ring-opening reactions under various conditions, potentially leading to the formation of more complex structures. This property is exploited in many organic synthesis applications.
  • Molecular Interactions: The bulky phenyl and methyl substituents allow for interesting steric interactions, which can influence the compound's overall reactivity and biological activity.

In summary, aziridin-1-yl-[3-[bis(2-chloroethyl)amino]-4-methyl-phenyl]methanone stands out not just for its structure, but also for its potential implications in medicinal chemistry and organic synthesis. This compound is a prime example of how seemingly simple structures can lead to complex and valuable chemical interactions.

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