Amlodipine

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Identification

Molecular formula
C20H25ClN2O5
CAS Number
88150-42-9
IUPAC Name
benzyl-[2-[5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carbonyl]oxyethyl]-methyl-ammonium
Molecular Weight
408.88g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.1850g/cm3
Synonyms
HMS1361F11
Interesting facts

Interesting Facts about Benzyl-[2-[5-Methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carbonyl]oxyethyl]-methyl-ammonium

This compound, known for its complex structure and biological activity, is a derivative of dihydropyridine, a class of compounds that has garnered significant attention in medicinal chemistry.

Key Characteristics:

  • Pharmacological Potential: Compounds featuring the dihydropyridine skeleton are widely recognized for their cardiovascular properties, particularly as calcium-channel blockers. This may position this compound as a candidate for treating hypertension.
  • Functional Groups: The presence of multiple functional groups, including methoxycarbonyl and nitro groups, suggests diverse chemical reactivity and potential for further modification, making it a versatile core for medicinal applications.
  • Research Insights: Dihydropyridine derivatives have been the subject of various studies, with some research indicating their effectiveness in managing conditions like angina pectoris and arrhythmias.

Synthetic Applicability:

The intricate design of this compound allows for various synthetic pathways, enabling chemists to explore different methodologies while enhancing yields and purities. Additionally, derivatives can be created through selective modifications, potentially improving drug-like properties.

Quote from Research:

“Compounds that display dihydropyridine frameworks often exhibit a dual role as both therapeutic agents and essential intermediates in synthetic organic chemistry.”

In conclusion, benzyl-[2-[5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carbonyl]oxyethyl]-methyl-ammonium represents a noteworthy link between organic chemistry and pharmacology, highlighting the significance of structural diversity in the development of new therapeutic agents.

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