Clotrimazole

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Identification

Molecular formula
C22H17ClN2O
CAS Number
23593-75-1
IUPAC Name
dimethyl-[3-[5-nitro-2-[2-(1-piperidyl)ethyl]benzimidazol-1-yl]propyl]ammonium;chloride
Molecular Weight
274.19g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2490g/cm3
Appearance
is common.
Synonyms
Benzimidazole, 1-(3-(dimethylamino)propyl)-5-nitro-2-(2-piperidinoethyl)-, hydrochloride
Interesting facts

Interesting Facts About Dimethyl-[3-[5-Nitro-2-[2-(1-Piperidyl)ethyl]benzimidazol-1-yl]propyl]ammonium; Chloride

This compound exhibits fascinating characteristics that make it stand out in the field of medicinal chemistry. Here are some key points to consider:

  • Pharmacological Relevance: The presence of a benzimidazole ring is particularly noteworthy, as compounds containing this structure are often investigated for their antiviral and anticancer properties.
  • Functional Groups: The inclusion of a nitro group on the aromatic system can enhance the compound's biological activity by serving as a potential pharmacophore, highlighting the importance of functional group manipulation in drug design.
  • Piperidine Incorporation: The piperidyl group is known for its ability to increase the solubility and bioavailability of drugs, making this compound potentially effective in pharmaceutical applications.
  • Structure-Activity Relationship (SAR): Understanding the relationship between the structure of this compound and its biological activity offers valuable insights for further development. The structural complexity can lead to a range of activities, sparking interest in collaborative studies with biochemists.
  • Transport Mechanisms: Chloride ions play a crucial role in various physiological processes. As a quaternary ammonium compound, it may interact with various cell membrane systems, offering additional avenues for research into drug delivery methods.

In conclusion, dimethyl-[3-[5-nitro-2-[2-(1-piperidyl)ethyl]benzimidazol-1-yl]propyl]ammonium; chloride serves as an excellent example of how structural complexity can lead to diverse applications in therapeutic development. The exploration of this compound may further our understanding of its mechanisms and actions, paving the way for innovative medical therapies.

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