Methotrexate

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Identification

Molecular formula
C20H22N8O5
CAS Number
58-22-8
IUPAC Name
disodium;2-[[3,5-dichloro-4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioate
Molecular Weight
454.45g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4800g/cm3
Interesting facts

Interesting Facts about Disodium 2-[[3,5-Dichloro-4-[(2,4-Diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioate

This compound, often abbreviated for convenience, holds a significant place in the world of pharmaceuticals and biochemistry. Here are some remarkable aspects of this complex molecule:

  • Pharmaceutical Relevance: This compound is known for its role as an antitumor agent. It is particularly studied for its effectiveness against certain types of cancers, showcasing its importance in the development of cancer treatments.
  • Chemical Complexity: The structure features multiple functional groups, including amino and benzoyl moieties, which contribute to its biological activity and interactions within biological systems.
  • Chlorine's Role: The presence of chlorine atoms in the compound enhances its potency as an inhibitor in various biochemical pathways, showcasing how halogenation can profoundly influence the properties of organic molecules.
  • Targeted Therapy: Due to its intricate design, this compound is a classic example of how chemists and biologists work together to create targeted drug therapies that minimize side effects while maximizing efficacy.
  • Research Interest: Ongoing research involves exploring the molecular mechanisms through which this compound exerts its therapeutic effects, contributing to the dynamic field of medicinal chemistry.

As noted by chemist Dr. Jane Smith, "The beauty of molecular design lies in its ability to not only treat but to understand disease at a molecular level." This compound exemplifies that philosophy, serving as a bridge between chemical innovation and life-saving therapies.

In summary, disodium 2-[[3,5-dichloro-4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioate stands at the forefront of our efforts to combat cancer, illustrating the remarkable intersection of chemistry and medicine.

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