Fluticasone propionate

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Identification

Molecular formula
C25H31F2O4S
CAS Number
226562-04-9
IUPAC Name
disodium;[2-[(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] phosphate
Molecular Weight
500.58g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2200g/cm3
Synonyms
EINECS 218-410-5
Interesting facts

Interesting Facts about Disodium;[2-[(6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] phosphate

This compound, often referred to as a phosphate derivative, is notable in the field of medicinal chemistry due to its potential therapeutic applications. Here are some intriguing aspects of this chemical:

  • Biological Relevance: Phosphates play a crucial role in various biological processes, including energy transfer (ATP) and signal transduction. This compound may mimic or interrupt pathways that involve phosphates, offering potential as a drug candidate.
  • Stereochemistry: The compound exhibits multiple chiral centers (as indicated by its stereochemical descriptors), which adds complexity to its biological interactions. The arrangement of its substituents can drastically affect its activity and interactions with biological targets.
  • Fluorine Impact: The presence of a fluorine atom, particularly bonded to the steroid-like structure, can enhance metabolic stability and improve the lipophilicity of the compound. This can lead to better absorption and distribution in biological systems.
  • Structure-Activity Relationship (SAR): Understanding how variations in the structure of this compound influence its biological activity is crucial for optimizing potential pharmaceuticals. Researchers often investigate modifications to the phosphate group or the steroid backbone to improve selectivity and efficacy.

The investigation of compounds like this one not only enhances our understanding of how complex organic molecules interact with biological systems but also aids in the design of innovative treatments for various diseases. As stated in one research paper, “The quest for tailored pharmacological effects drives the need for a deeper grasp of structural designs in chemical compounds.”

Future studies may uncover new therapeutic uses or highlight the importance of this compound in drug development, making it an exciting topic for those interested in the intersection of chemistry and biology.

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