Flurazepam

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Identification

Molecular formula
C21H23ClFN3O3
CAS Number
17617-23-1
IUPAC Name
ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylate
Molecular Weight
387.88g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4000g/cm3
Synonyms
ethyl loflazepate
Interesting facts

Interesting Facts about Ethyl 7-Chloro-5-(2-Fluorophenyl)-2-oxo-1,3-Dihydro-1,4-benzodiazepine-3-carboxylate

This compound is part of the benzodiazepine family, which is renowned for its therapeutic properties. Here are some fascinating insights into this particular derivative:

  • Structure and Stability: The presence of both a chlorine and a fluorine atom in the structure contributes to its unique pharmacological profile and can enhance stability against metabolic degradation.
  • Biological Activity: Compounds structurally related to benzodiazepines are often known for their ability to modulate the action of neurotransmitters in the brain, particularly influencing the gamma-aminobutyric acid (GABA) receptors, which makes them effective anxiolytics and sedatives.
  • Chemical Synthesis: The synthesis of this compound may involve multi-step reactions, often including nucleophilic substitutions and cyclization reactions, showcasing the complexity of synthetic organic chemistry.
  • Potential Applications: Beyond their use in treating anxiety and insomnia, benzodiazepines are also being explored for their neuroprotective effects and potential use in various chronic diseases.
  • Scientific Research: The ongoing study of compounds like this one highlights the importance of structure-activity relationships (SAR) in medicinal chemistry, guiding researchers in the design of new therapeutic agents.

As a part of the ongoing exploration in drug discovery, understanding the nuances of compounds like ethyl 7-chloro-5-(2-fluorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepine-3-carboxylate not only reveals their potential in clinical applications but also enriches our knowledge of chemistry at a molecular level.

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