Tenofovir disoproxil fumarate

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Identification

Molecular formula
C19H30N5O10P
CAS Number
202138-50-9
IUPAC Name
[hydroxy-[[3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy]phosphoryl] [3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] hydrogen phosphate
Molecular Weight
635.52g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5000g/cm3
Synonyms
TDP-Glucose
Interesting facts

Interesting Facts about Hydroxy-[[3-Hydroxy-5-(5-Methyl-2,4-Dioxo-Pyrimidin-1-Yl)Tetrahydrofuran-2-Yl]Methoxy]Phosphoryl][3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydropyran-2-Yl] Hydrogen Phosphate

This intriguing compound showcases a complex structure featuring various functional groups that give it unique properties and potential applications in different fields. Here are some engaging facts to consider:

  • Multi-functional capabilities: This compound comprises multiple functional groups, such as hydroxyl and phosphonate groups, which may contribute to its potential as a bioactive molecule. Such functionality often plays a crucial role in biological activities.
  • Drug design: The integration of pyrimidine and tetrahydrofuran moieties suggests that this compound could be a valuable lead in the design of new pharmaceutical agents. Molecules with similar structures have shown promise in targeting various diseases.
  • Studying enzyme interactions: The presence of phosphate groups can facilitate interaction with biological enzymes, making this compound a great candidate for studying enzyme inhibition and activation, particularly within metabolic pathways.
  • Structure-activity relationship (SAR): As a student of chemistry, you might find it fascinating to explore how alterations in the molecule's structure (like changing functional groups) influence its biological activity, paving the way for the development of more effective therapeutic agents.
  • Potential roles in nucleic acid chemistry: Given its phosphonate functionalities, this compound may be involved in nucleic acid chemistry, particularly in the formulation of phosphoramidate prodrugs that aim to enhance the delivery and efficacy of nucleic acid-based therapeutics.

In conclusion, hydroxy-[[3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy]phosphoryl][3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] hydrogen phosphate stands as a testament to the complexity and versatility of chemical compounds. Its potential applications in medicinal chemistry and biochemistry make it an exciting subject for further study and exploration.

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