Everolimus

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Identification

Molecular formula
C53H83NO14
CAS Number
159351-69-6
IUPAC Name
methyl (1R,9R,10S,11R,12R,19R)-11-acetoxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate
Molecular Weight
958.22g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.0000g/cm3
Synonyms
vincristine
Interesting facts

Interesting Facts about Methyl (1R,9R,10S,11R,12R,19R)-11-acetoxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate

This compound is a fascinating example of complex organic chemistry, exemplifying the intricate relationships found in bioactive molecules. As a derivative of a larger parent structure, it features multiple stereocenters, which contributes to its unique spatial configuration. Here are some intriguing aspects of this compound:

  • Structural Complexity: With its numerous rings and substituents, it represents a highly intricate molecular architecture, making it a subject of interest for synthetic chemists.
  • Biological Relevance: Compounds with similar structures often demonstrate significant biological activity, making them valuable in medicinal chemistry, particularly in the development of pharmaceuticals.
  • Stereochemistry: The various stereogenic centers not only provide diverse conformational possibilities but also profoundly influence the compound's interaction with biological targets.
  • Functional Groups: The presence of functional groups such as acetoxy and methoxy serves as key points for further chemical reactions or modifications, enhancing its utility in drug design.

As stated in the literature, "The interplay of structure and function in complex organic molecules is a cornerstone of modern medicinal chemistry." This compound encapsulates that notion, showcasing how detailed understanding and manipulation of molecular structures can lead to breakthroughs in therapeutic possibilities.

In the sphere of research, compounds like this one are vital for advancing our understanding of organic synthesis techniques, particularly in the context of natural product chemistry. Scientists continually explore the potential therapeutic applications of such complex structures, promising exciting developments in the field.

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