Topotecan

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Identification

Molecular formula
C23H23N3O5
CAS Number
123948-87-8
IUPAC Name
N-(2-aminophenyl)-6-[5-hydroxy-1,3-dioxo-6-(1-piperidylmethyl)benzo[de]isoquinolin-2-yl]hexanamide
Molecular Weight
421.45g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3790g/cm3
Synonyms
CHEMBL329745
Interesting facts

Interesting Facts about N-(2-Aminophenyl)-6-[5-hydroxy-1,3-dioxo-6-(1-piperidylmethyl)benzo[de]isoquinolin-2-yl]hexanamide

This complex organic compound belongs to a fascinating class of molecules known for their diverse applications in medicinal chemistry. Here are some intriguing insights about it:

  • Structure Complexity: The compound exhibits a multi-functional structure, featuring an amino group, hydroxyl groups, and a piperidine moiety, which contribute to its potential activity and reactivity.
  • Potential Therapeutic Uses: Compounds of this nature are often investigated for their roles in therapeutic settings, particularly in the realm of cancer treatment and neuroprotection, due to their ability to modulate various biochemical pathways.
  • Isoquinoline Derivative: The presence of the benzo[de]isoquinoline framework is particularly noteworthy, as isoquinoline compounds are known for their rich pharmacological properties, including anti-inflammatory and analgesic effects.
  • Development of Drug Candidates: Each component of this molecule can be tweaked to enhance efficacy or reduce toxicity, making it an excellent candidate for drug development. Fallacious molecules can be tailored by altering functional groups.
  • Research Significance: Studies involving such compounds can lead to a deeper understanding of their mechanism of action, toxicity profiles, and interactions with biological targets, paving the way for innovative therapies.

Overall, N-(2-aminophenyl)-6-[5-hydroxy-1,3-dioxo-6-(1-piperidylmethyl)benzo[de]isoquinolin-2-yl]hexanamide embodies the intersection of structural chemistry and biology, highlighting the intricate relationships between molecular architecture and biological activity.

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