Paracetamol

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Identification

Molecular formula
C8H9NO2
CAS Number
103-90-2
IUPAC Name
N-(3-amino-4-methyl-phenyl)acetamide
Molecular Weight
151.17g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2630g/cm3
Synonyms
N-(3-Amino-4-methylphenyl)acetamide
Interesting facts

Interesting Facts about N-(3-amino-4-methyl-phenyl)acetamide

N-(3-amino-4-methyl-phenyl)acetamide, often referred to by its systematic name or simply as an acetamide derivative, is a fascinating compound in the realm of organic chemistry. Here are some intriguing aspects of this compound:

  • Biological Relevance: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of analgesic and anti-inflammatory drugs. Its structural features can enhance biological activity or alter pharmacokinetics.
  • Amine Group Influence: The presence of the amino group in this derivative plays a critical role in determining its reactivity and interaction with other molecules. Amine-containing compounds are often involved in hydrogen bonding, which can greatly affect their solubility and reactivity.
  • Structure-Activity Relationship (SAR): The unique arrangement of the amino and methyl groups on the phenyl ring influences the compound's biological properties. In studying SAR, chemists can predict how modifications to its structure may enhance or inhibit its activity.
  • Synthesis: The compound can be synthesized through various methods, including nucleophilic substitution reactions. Understanding the mechanisms behind these syntheses is crucial for chemists aiming to create more efficient pathways in drug design.
  • Interdisciplinary Studies: Research on N-(3-amino-4-methyl-phenyl)acetamide often overlaps with fields such as medicinal chemistry and toxicology. This makes it a valuable compound for interdisciplinary studies, offering insights that can lead to novel therapeutic agents.

In conclusion, N-(3-amino-4-methyl-phenyl)acetamide exemplifies the intricate relationship between structure and function in pharmaceuticals. As we continue to explore its properties, we uncover the vast potential it holds for improving therapeutic outcomes and developing new medicinal compounds.

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