N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine

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Identification

Molecular formula
C16H14BrN3O2
CAS Number
179688-29-0
IUPAC Name
N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine
Molecular Weight
397.21g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4870g/cm3
Synonyms
153436-54-5
Interesting facts

Interesting Facts about N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine

N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine is an intriguing chemical compound that belongs to the quinazolinamine class, known for its pharmaceutical potential and diverse biological activities. Here are some captivating insights into this compound:

  • Structure Complexity: The compound features a quinazoline core, which is a bicyclic structure that consists of a benzene ring fused to a pyrimidine ring. This unique structure provides a platform for various substitutions that can significantly influence its biological activity.
  • Biological Significance: Compounds that share a similar scaffold to N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine have been studied for their potential in treating a variety of diseases, including cancers and inflammatory disorders.
  • Substituent Influence: The presence of the 3-bromophenyl and dimethoxy groups is of particular interest. The bromine atom can enhance binding interactions with biological targets, while the dimethoxy groups can affect solubility and pharmacokinetics.
  • Synthetic Pathways: The synthesis of quinazolinamines often involves multi-step reactions that may include reactions like cyclization, coupling, or functionalization, making the development of this compound a fascinating study in synthetic organic chemistry.
  • Keywords in Research: Researchers often emphasize the terms "antitumor," "antimicrobial," and "cognitive disorder modulation" in studies involving similar quinazoline derivatives—a reflection of their broad therapeutic applications.

In summary, N-(3-bromophenyl)-6,7-dimethoxy-quinazolin-4-amine presents a rich field for exploration in medicinal chemistry, with its complex structure and diverse potential benefits to human health. As the quest for new pharmaceutical agents continues, compounds like this one are at the forefront of modern medicinal research.

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