Cl-Quinazolin-4-amine

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Identification

Molecular formula
C17H14ClN3O2
CAS Number
82916-45-2
IUPAC Name
N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine
Molecular Weight
327.76g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3571g/cm3
Synonyms
153436-53-4
Interesting facts

Exploring N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine

N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine is a fascinating compound with a rich potential in medicinal chemistry. Here are some intriguing facts about this molecule:

  • Pharmacological Potential: This compound belongs to the quinazoline family, which is known for its various biological activities. Quinazolines have been reported to possess antitumor, antiviral, and antimicrobial properties.
  • Chlorine Substitution: The presence of the 3-chloro group on the phenyl ring greatly influences the compound's electronic properties, enhancing its ability to interact with biological targets.
  • Methoxy Groups: The dimethoxy substituents at positions 6 and 7 are known to contribute to the lipophilicity of the compound, affecting its absorption and distribution in biological systems.
  • Structure-Activity Relationship (SAR): Understanding how different substituents, like the chlorine and methoxy groups, alter the compound's efficacy is critical in drug design. It provides insights into optimizing therapeutic agents.
  • Pivotal in Research: Compounds like this serve as key intermediates for synthesizing more complex molecules, making them valuable in ongoing research for developing new drugs.

In summary, N-(3-chlorophenyl)-6,7-dimethoxy-quinazolin-4-amine showcases the intricate balance of chemical structure and biological function. Such compounds are essential in the search for new therapeutic agents that can combat various diseases.

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