Amsacrine

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Identification

Molecular formula
C21H19N3O3S
CAS Number
51264-14-3
IUPAC Name
N-[4-(acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide
Molecular Weight
393.46g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3400g/cm3
Appearance
when exposed to light, as it is known to be photoreactive.
Synonyms
amsacrine
Interesting facts

Interesting Facts about N-[4-(Acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide

N-[4-(Acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide is an intriguing compound that has garnered attention in the field of medicinal chemistry. Here are some noteworthy facts:

  • Versatile Applications: This compound possesses properties that make it a potential candidate for pharmaceutical applications, particularly in the realm of cancer research and treatment due to its unique molecular structure.
  • Mechanism of Action: The acridine moiety in the compound is reminiscent of many DNA-acting drugs. These types of compounds can intercalate into DNA, which may lead to an inhibition of cancer cell growth.
  • Sulfonamide Feature: The presence of the sulfonamide group enhances the compound's solubility and can improve its pharmacokinetic properties, making it easier for the drug to reach its targets in the body.
  • Research Interest: Studies on this compound are still ongoing, as researchers are keen to explore its efficacy and mechanism. As highlighted by one researcher: "Compounds like this hold the key to unlocking new cancer therapies."
  • Pioneering Structure: The combination of acridine and methanesulfonamide provides a framework for further modifications, thereby enabling the development of more potent derivatives useful in various medical fields.

In summary, N-[4-(Acridin-9-ylamino)-3-methoxy-phenyl]methanesulfonamide represents a significant topic of study in drug design and development. Its unique structural characteristics and potential applications in targeting cancer cells stand as a testament to the innovative nature of modern chemistry.

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