Thiothiamine

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Identification

Molecular formula
C14H22N4O3S2
CAS Number
59-30-3
IUPAC Name
N-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-N-[4-hydroxy-1-methyl-2-(tetrahydrofuran-2-ylmethyldisulfanyl)but-1-enyl]formamide
Molecular Weight
338.40g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4600g/cm3
Synonyms
N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{5-hydroxy-3-[(oxolan-2-ylmethyl)disulfanyl]pent-2-en-2-yl}formamide
Interesting facts

Interesting Facts about N-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-N-[4-hydroxy-1-methyl-2-(tetrahydrofuran-2-ylmethyldisulfanyl)but-1-enyl]formamide

This compound boasts a fascinating structure, combining various functional groups and motifs that highlight its potential applications in medicinal chemistry and drug development. Here are some key points of interest:

  • Diverse Functionalities: The presence of an amino group, a hydroxyl group, and a disulfide linkage gives this compound a rich chemistry, making it a potential candidate for drug design.
  • Pyrimidine Backbone: The inclusion of a pyrimidine ring in its structure suggests possible antiviral or anticancer properties, as many drugs targeting nucleic acid synthesis contain similar frameworks.
  • Disulfide Bonds: The incorporation of disulfide bonds in the tetrahydrofuran unit may play a role in redox reactions within biological systems, potentially influencing its pharmacokinetic properties.
  • Unique Linker System: The specially designed linker that connects the pyrimidine and the butenyl group could enhance the compound’s affinity to specific biological targets, enhancing its efficacy.

As a chemistry student, one might find it intriguing that this compound can serve as a model for studying complex interactions in biological systems. Its various substituents may yield different biological activities, prompting further investigation into structure-activity relationships (SAR). Researchers often investigate how small changes in the structure can lead to significant differences in potency and selectivity against disease targets.

"The beauty of medicinal chemistry lies in its complexity and the promise of discovery," resonates well with the exploration of such molecular architectures.

In summary, while this compound may not be widely known, its structural intricacies present numerous avenues for research, emphasizing the critical balance of structure and function in the design of effective therapeutic agents.

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