Schiff base derived from 1H-indole-3-carbaldehyde and 4-chloroaniline

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Identification

Molecular formula
C15H11ClN2
CAS Number
13676-22-3
IUPAC Name
N-(4-chlorophenyl)-1-(1H-indol-3-yl)methanimine
Molecular Weight
251.72g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2560g/cm3
Synonyms
3-(N-p-Chlorophenylformimidoyl)indole
Interesting facts

Interesting Facts about N-(4-chlorophenyl)-1-(1H-indol-3-yl)methanimine

N-(4-chlorophenyl)-1-(1H-indol-3-yl)methanimine, commonly recognized as a significant chemical compound in pharmaceutical research, holds a prominent place in the study of medicinal chemistry. Here are some engaging insights into this compound:

  • Anticancer Potential: This compound is part of a structural class known for its potential anticancer properties. Studies have indicated that molecules with indole moieties may exhibit significant bioactivity against various cancer cell lines.
  • Chlorophenyl Influence: The substitution of a chlorine atom on the phenyl ring can enhance the pharmacological profile of the compound, making it more potent or selective in action. Chlorinated compounds often display modified solubility and biological properties, which are critical in drug design.
  • Indole Backbone: The indole structure is a hallmark in many natural products and synthetic drugs, playing a crucial role in neurotransmitter functioning and showing promise in various neurological disorders.
  • Synthetic Pathways: The synthesis of this compound is of great interest to chemists, not only for its potential applications but also due to its intricate synthesis routes that highlight the importance of regioselectivity and chirality in organic synthesis.
  • Research Implications: Continued investigation into compounds like N-(4-chlorophenyl)-1-(1H-indol-3-yl)methanimine can lead to the development of novel therapeutic agents, reflecting the dynamic interplay between chemistry and medicine.

In summary, the exploration of N-(4-chlorophenyl)-1-(1H-indol-3-yl)methanimine not only sheds light on its potential uses but also exemplifies the broader themes in chemical research and its applications in improving human health.

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