N-(4-chlorophenyl)benzenesulfonamide

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Identification

Molecular formula
C12H10ClNO2S
CAS Number
35303-76-5
IUPAC Name
N-(4-chlorophenyl)benzenesulfonamide
Molecular Weight
281.73g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.4370g/cm3
Synonyms
N-(4-CHLOROPHENYL)BENZENESULFONAMIDE
Interesting facts

Interesting Facts about N-(4-chlorophenyl)benzenesulfonamide

N-(4-chlorophenyl)benzenesulfonamide, widely studied for its potential therapeutic applications, represents a fascinating class of chemical compounds known as sulfonamides. These compounds have a unique structure that contributes to their diverse biological activities.

Key Features

  • Antimicrobial Properties: Many sulfonamides, including this one, have been explored for their antimicrobial effects, providing a base for the development of antibiotics.
  • Role in Drug Development: Due to their chemical versatility, sulfonamides have been pivotal in medicinal chemistry, leading to the synthesis of numerous pharmaceutical agents.
  • Biochemical Mechanism: The sulfonamide group can mimic p-aminobenzoic acid (PABA), inhibiting bacterial folate synthesis, which is vital for DNA and RNA production.

Applications

  1. Current research is examining N-(4-chlorophenyl)benzenesulfonamide's role in treating bacterial infections.
  2. There is ongoing interest in its antitumor properties, with studies exploring its effectiveness against certain types of cancer cells.
  3. Its use as a building block in organic synthesis opens doors for developing novel compounds in various fields.

Please note: While investigating this compound, researchers must pay attention to potential side effects such as hypersensitivity reactions, which highlight the importance of thorough pharmacological evaluations.

In Conclusion

The importance of N-(4-chlorophenyl)benzenesulfonamide in both research and application cannot be overstated. Its impact resonates across multiple fields including pharmaceuticals, biochemistry, and synthetic organic chemistry, making it a compound of great interest in scientific explorations.

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