Quinoline-6-carboxamide

Molecular formula: C₁₁H₁₀N₂O
CAS Number: 61995-34-6
IUPAC Name: N-(6-quinolyl)acetamide
Molecular Weight: 186.21g/mol
Melting Point: (Celsius)
Boiling Point: (Celsius)
Density: 1.3060g/cm3
Synonyms: N-(quinolin-6-yl)acetamide

Interesting facts

Interesting Facts about N-(6-quinolyl)acetamide

N-(6-quinolyl)acetamide is a fascinating compound that boasts a variety of notable features and applications in the field of chemistry.

Chemical Structure

The compound is structured around a quinoline base, specifically 6-quinoline, which is known for its aromatic characteristics. This unique structure provides:

Stability: The presence of an aromatic system lends stability to the compound.
Electron-rich nature: The nitrogen atom in the quinoline ring contributes to its electron density, making it useful in various chemical reactions.

Applications in Research

N-(6-quinolyl)acetamide has gained attention in different areas of research, including:

Medicinal Chemistry: This compound's derivatives are being investigated for potential antitumor and antimicrobial activities, highlighting its promise in drug development.
Coordination Chemistry: The nitrogen lone pair can act as a ligand, forming complexes with metals that are vital for understanding catalytic processes.

Quinolines in Nature

Quinolines, including N-(6-quinolyl)acetamide, are often found in various natural products. They can:

Serve as alkaloids, which are organic compounds containing basic nitrogen atoms.
Possess various biological activities, allowing researchers to explore their potential health benefits.

Research Challenges

Despite its potential, working with N-(6-quinolyl)acetamide can present difficulties:

Synthesis Challenges: The synthesis of quinoline-based compounds often requires careful control of reaction conditions.
Toxicity Concerns: Some quinoline derivatives can exhibit toxicity, necessitating thorough safety assessments in research contexts.