Amsacrine

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Identification

Molecular formula
C22H19Cl2N3O·2HCl
CAS Number
51264-14-3
IUPAC Name
N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-acridin-9-yl)pentane-1,4-diamine;dihydrochloride
Molecular Weight
457.82g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
2.5000g/cm3
Synonyms
Quinacrine mustard dihydrochloride
Interesting facts

Interesting Facts about N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-acridin-9-yl)pentane-1,4-diamine; dihydrochloride

N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-acridin-9-yl)pentane-1,4-diamine; dihydrochloride is a compound that presents a fascinating intersection between organic chemistry and medicinal applications. Here are some key points to highlight its significance:

  • Pharmacological Relevance: This compound is linked to notable research in the field of oncology due to its cytotoxic properties. The presence of acridine moieties suggests potential applications in antitumor therapies.
  • Mechanism of Action: Compounds with similar structures often function by interfering with DNA replication processes in cancer cells, thus slowing down or stopping tumor growth.
  • Structural Complexity: The intricate arrangement of both chloroethyl and methoxy groups along with the acridine backbone contributes to the compound's unique pharmacological activities, making it an interesting subject for further study.
  • Derivative Studies: The versatility of this compound allows for the synthesis of various derivatives, which can be tailored to enhance efficacy and reduce toxicity in cancer treatment regimens.
  • Historical Insights: The development of compounds with acridine structures dates back to the early 20th century and continues to inspire research for new therapeutic agents.

As a single entity within a broader category of anticancer compounds, N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-acridin-9-yl)pentane-1,4-diamine; dihydrochloride represents the complexities and potential of synthetic medicinal chemistry. Its ongoing study not only enhances our understanding of cancer treatments but also paves the way for innovative drug discovery.

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