Nifedipine
- Molecular formula
- C17H18Cl2N2O6
- CAS Number
- 21829-25-4
- IUPAC Name
- O5-ethyl O3-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
- Molecular Weight
- 346.33g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.4200g/cm3
- Synonyms
- felodipine
Identification
Interesting Facts about O5-ethyl O3-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
This compound is a unique member of the dihydropyridine family, known for its interesting pharmacological properties. Dihydropyridines are widely studied for their ability to act as calcium channel blockers, which makes them important in the treatment of cardiovascular diseases. Below are some intriguing aspects of this particular dihydropyridine derivative:
- Pharmacological Potential: Compounds like this one often demonstrate potential as antihypertensive agents. The incorporation of dichlorophenyl groups is known to enhance their activity.
- Versatile Synthesis: The synthetic pathway leading to this compound usually involves steps that allow for high versatility, accommodating various substitutions that can modulate its physical and chemical properties.
- Chirality and Isomerism: The presence of multiple chiral centers offers opportunities for the exploration of stereoisomerism, which can vastly alter the biological activity of each isomer.
- Research Implications: This compound has been a subject of research in designing selective drugs targeting specific ion channels, showcasing the importance of structure-activity relationships in medicinal chemistry.
As a chemistry student or professional, studying such complex compounds can greatly enhance one's understanding of organic synthesis and drug design. The careful manipulation of functional groups in dihydropyridines is not just an exercise in synthetic chemistry but a crucial step towards developing effective therapeutic agents. As one researcher noted, "A small change in structure can lead to dramatically different biological effects.”
In summary, O5-ethyl O3-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate stands as an exemplary model of how organic chemistry can intersect with medicinal applications, acting as a bridge between theoretical investigation and practical health solutions.