4-Pyridinethiol

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Identification

Molecular formula
C5H5NS
CAS Number
142-65-4
IUPAC Name
pyridine-4-thiol
Molecular Weight
111.17g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.2210g/cm3
Appearance
can change color upon exposure to air due to oxidation.
Interesting facts

Interesting Facts About Pyridine-4-thiol

Pyridine-4-thiol, also known as 4-mercaptopyridine, is a fascinating compound with several intriguing characteristics. This heterocyclic organic compound contains a sulfur atom within its molecular structure, which significantly influences its chemical behavior.

Chemical Structure and Characteristics

One of the remarkable aspects of pyridine-4-thiol includes:

  • Functional Group: The presence of a thiol (-SH) group makes pyridine-4-thiol a potent nucleophile, which allows it to engage in various chemical reactions.
  • Heterocyclic Nature: Being part of the pyridine family, its aromatic properties contribute to its stability and reactivity, making pyridine-4-thiol a versatile compound in synthetic organic chemistry.

Applications in Industry and Research

Pyridine-4-thiol has various applications, including:

  • Synthesis of Organosulfur Compounds: Its thiol group enables the synthesis of a wide range of organosulfur compounds, which are useful in agrochemicals and pharmaceuticals.
  • Ligand Formation: It can act as a ligand in coordination chemistry, forming complexes with transition metals, which are essential for catalytic processes.
  • Research Applications: Its unique properties make it a compound of interest in biological studies, particularly in investigating enzyme active sites and mechanisms.

Health and Safety Considerations

While pyridine-4-thiol has useful applications, it is crucial for researchers to handle it with care:

  • Harmful Effects: Exposure can lead to irritation of the skin and eyes.
  • Safe Handling: Use protective equipment and follow safety protocols to minimize any health risks associated with its use.

In conclusion, pyridine-4-thiol is more than just a simple thiol compound; it plays a crucial role in various areas of chemistry and industry. Its unique properties and versatility make it an interesting subject of study for chemists and researchers alike.

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